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Botox vs Dysport vs Xeomin

What is the difference between Botox, Dysport, and Xeomin?

Botox Cosmetic (manufactured by Allergan Pharmaceuticals), Dysport (manufactured by Medicis Pharmaceuticals), and Xeomin (manufactured by Merz Pharmaceuticals) are highly purified forms of a neurotoxin (botulinum Type A) produced by the bacterium Clostridium Botulinum. The purification processes produce a slightly different chemical form of the toxin (onabotulinumtoxinA for Botox, abobotulinumtoxinA for Dysport, and incobotulinumtoxinA for Xeomin) but the effects on the human nervous system are virtually identical. Skin Care By Design currently offers Botox and Dysport because there are situations in which one product is slightly preferable to the other. We do not offer Xeomin because it is administered and acts the same as Botox.

Botox and Xeomin, have exactly the same units, are reconstituted and administered in exactly the same way, and take effect in the same amount of time, which makes it relatively easy for a practice that uses Botox to add or switch to Xeomin. Because everything about the treatment process is identical, Botox and Xeomin prices can be compared directly. The difference between Xeomin and Botox is that the Botox molecule is stabilized with a protein "wrapper" while the Xeomin molecule is "naked". The smaller Xeomin molecule is less likely to stimulate the development of antibodies. However, only about 1 in 10,000 Botox patients develop these antibodies so a small reduction in this rate is not significant.

Dysport has different units than Botox and Xeomin, it is reconstituted differently, and it takes effect one to three days faster. The injection amounts and techniques are different for the same treatment areas, which makes it more difficult for a practice that uses Botox or Xeomin to add or switch to Dysport. It also makes it more difficult to compare prices.

There are a number of questions that have received a lot of attention and some disagreement:


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